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Clinicians can diagnose high urine calcium by asking patients to collect urine for 24 h or to provide a random urine specimen. In this study, random urine calcium levels were not as accurate as those from the h collection. Clinicians should only use h collections to diagnose high urine calcium. Clinicians must use the 24HUC to diagnose hypercalciuria in postmenopausal women. Hypercalciuria can cause nephrolithiasis and osteoporosis [ 1 ], and its diagnosis influences management of these conditions [ 2 ]. Clinicians can diagnose hypercalciuria by measuring h urine calcium 24HUC levels, an approach considered as the gold standard [ 3 , 4 ].
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